|
|
Basenji Health InformationIt is known that all breeds of dogs have some inherited diseases, unfortunately.
We believe it is our responsibility to screen all breeding stock, prior to engaging in any litters. People looking
into purchasing a Basenji, (or any breed of dog), should educate themselves in which diseases are applicable, and then quiz
the breeder/s, that they are interested in, as to what health testing has been done. It’s recommended that you see the
copies of all health results of the breeder/dogs you may be looking at.
The following is a list of disease that
affects the Basenji, in no particular order: Fanconi
Syndrome Description Fanconi
Syndrome is quite prevalent in the Basenji, but, it is also seen in other breeds and humans as well. It is where the proximal
renal tubules, of the kidneys, dont reabsorb nutrients and electrolytes back into the body, so therefore these will ‘spill’
into the urine. The body then loses these vital nutrients needed for normal function. Some
of the signs and symptoms include: - Increased thirst, increased urination, weight loss, muscle wasting, weakness, dehydration,
coat changes etc. It should be noted here that some of these signs and symptoms are seen in Diabetes, and until recently,
many Basenji’s were misdiagnosed as such, often with disastrous and/or fatal consequences. This disease usually presents
after 3 years of age, but has been seen in younger and much older dogs.
While there is no cure
for this disease, so long as the dog is diagnosed early, treatment can give these dogs reasonable quality of life. Treatment
is usually centred on the replacement of the metabolic deficiencies, i.e. vitamin, mineral and bicarbonate, along with a high
protein diet. This treatment has been developed by Dr Steve Gonto, M.M. Sc PhD and more information can be found here.
If this disease is left untreated, it is fatal. Early detection is paramount. A DNA Linkage Test has been released
on July 14th 2007, at the University of Missouri. At this point in time it is only a linkage test, but we are hopeful that
we will be able to find the actual gene, very soon. There are 4 results that can be achieved: - Probable Clear, Probable Carrier,
Probable Affected, and finally, Probable Indeterminate. Probable Clear; the gene is not present in the dog. They will
not pass the gene on.
Probable Carrier; this dog has one copy only, of the gene.
Probable Affected; this dog has 2 copies of the gene. It will develop the disease and will always pass the gene
to offspring.
Probable Indeterminate; between Clear-Carrier. This dog should always be regarded
as a Carrier, when making breeding plans.
Breeding Pairs:- Parents; Fanconi Result; Clear x Clear= 100% clear puppies. Clear x Carrier= 50% clear, 50% carrier, on average. Clear x Affected= 100%
carrier. Carrier x Carrier= 25% clear, 50% carrier, 25% affected, on average. Carrier x Affected= 50% carrier, 50%
affected, on average. Affected x Affected= 100% affected.
Haemolytic
Anaemia, (Also known as Pyruvate Kinase Deficiency Haemolytic Anaemia):-Thankfully this
disease has nearly been eliminated, due to thorough testing, by breeders, worldwide. H.A is where red blood cells
are destroyed too quickly. This is due to a lack of an enzyme, called Pyruvate Kinase, (P.K.). Signs and symptoms of the disease
include: - the dog tires easily and sleeps more, they may faint, usually have very pale/white gums and will often have ‘golden’
coloured faeces. Dogs will typically die by approximately 2-4 years of age.
A DNA test is available and results
are either clear, carrier or affected. There are a few carriers still in the gene pool world-wide, but thankfully this disease
is nearly eradicated.IPSID
HypothyroidismHypothyroidism
is low levels of Thyroid Hormone found in the blood stream. The thyroid basically controls the metabolism of most cells, in
the body. Unfortunately, Basenji’s appear to have quite a high incidence of this disease. The signs and symptoms vary
greatly, but will often include: - aggressiveness, weight gain, (or sometimes weight loss), lethargy, infertility, poor coat
condition, skin issues, temperature intolerance, (usually to cold), irregular heat cycles etc. There are many other signs
and symptoms that may present in the dog, so a thorough evaluation is needed by your Vet, if you suspect this to be a problem
in your dog. Treatment is with a thyroid supplement usually given daily, and affected dogs will usually respond very quickly
to treatment. Diagnosis is made via a blood test and it is usually recommended that a full thyroid panel is collected,
i.e. T3, Free T3, T4, Free T4, T3AA, T4AA, TSH, (although this is not always recommended), and finally TgAA. At the time that
I was testing my dogs for this, I was unable to get the complete test done in Australia, for a reasonable price, so I sent
my bloods here...Once the results are known we highly recommend that you send the results to Dr Jean Dodds. Dr Dodds has a
particular interest in Hypothyroidism in dogs, and in particular sighthounds. Her vast knowledge in this area is of particular
interest to Basenji lovers all around the world. Even if the bloods are taken elsewhere, Dr Dodds is more than happy to read
the results, and inform your Vet on an appropriate course of treatment, if need be.
Another test which should
be done is the TgAA, for Autoimmune Lymphocytic Thyroiditis. It is believed to be a genetic issue for Basenji’s. It
is a single gene disorder, and a recessive trait. A positive result will only be found in dogs which have the 2 genes. Negative
results will show no genes. Results are only positive or negative, they will not show carriers, unfortunately. It is advised
to test annually until 5-6 years, because if the autoantibodies are not present at this age, it’s unlikely to develop
the disease.
Hip/Elbow Dysplasia Hip
Dysplasia is where the hip socket is badly formed, or malformed, which will eventually lead to lameness, and finally arthritis.
It’s thought to be polygenic, with multiple genes involved in its expression. It can affect either one or both hips.
Whilst hip dysplasia is not too common in the Basenji, there have been some dysplastic dogs detected, of varying
degrees. Breeding stock should be tested, (via x-ray, then these x-rays need to be assessed, and graded by a radiographic
specialist),prior to being bred from.
Elbow Dysplasia is also an inherited disease, which primarily affect large
breed dogs. It’s not known to be a problem in the Basenji’s. Its characterised by varying degrees of elbow incongruity,
bony fragments and finally severe arthritic changes in the elbow region.
The reason I have mentioned it here in
the Basenji health section, is because when sedating/anaesthetising the dog for his hip x-rays, it is not a lot more expense
to have the elbows done at the same time.
IPSID :- (Immunoproliferative Small Intestine Disease) This
disease over the years has also been known as Basenji Diarrhoea Syndrome, Chronic Intractable Diarrhoea, Malabsorbtion Syndrome,
or finally Basenji Enteropathy. Basically IPSID is a type of inflammatory bowel disease, which results in the
dog not being able to absorb nutrients from its food. It is thought to be inherited, but other factors may also predispose
dogs to it i.e. physical or emotional stress.
Some of the signs and symptoms include; diarrhoea, weight loss,
increase or decrease appetite, flatulence, vomiting, depression, dry coat and skin, and finally hair loss. The type of symptoms
and their severity do differ from dog to dog. These dogs have good days and bad days. Prognosis is poor, although it’s
thought that Holistic Medicine does/can offer some relief to these dogs. Treatment is mostly aimed at treating the signs and
symptoms that the dog displays e.g. vitamin/mineral supplements, antibiotics, prednisolone and also a thorough investigation
of the dog’s diet, including an elimination diet.
IPSID :- (Immunoproliferative Small Intestine Disease) This
disease over the years has also been known as Basenji Diarrhoea Syndrome, Chronic Intractable Diarrhoea, Malabsorbtion Syndrome,
or finally Basenji Enteropathy. Basically IPSID is a type of inflammatory bowel disease, which results in the
dog not being able to absorb nutrients from its food. It is thought to be inherited, but other factors may also predispose
dogs to it i.e. physical or emotional stress.
Some of the signs and symptoms include; diarrhoea, weight loss,
increase or decrease appetite, flatulence, vomiting, depression, dry coat and skin, and finally hair loss. The type of symptoms
and their severity do differ from dog to dog. These dogs have good days and bad days. Prognosis is poor, although it’s
thought that Holistic Medicine does/can offer some relief to these dogs. Treatment is mostly aimed at treating the signs and
symptoms that the dog displays e.g. vitamin/mineral supplements, antibiotics, prednisolone and also a thorough investigation
of the dog’s diet, including an elimination diet.
Hernia’s An
umbilical hernia is quite a common problem in the Basenji’s. It is a condition in which abdominal contents protrude
through the abdominal wall, at the area of the umbilicus. It is often just the fat that protrudes. They are usually quite
small and will often decrease in size as the pup grows. They are usually not serious and can be reduced at the time a pup
is desexed, or undergoes any other type of anaesthesia. They are thought to be inherited. Inguinal hernias are
uncommon in the Basenji, but they do crop up occasionally. It occurs when the abdominal contents/fat protrude through the
inguinal rings, which is located at the inner fold of the rear leg, the groin area. If they are large enough they can affect
part of the intestinal loop, the bladder and/or uterus, so it is important that they are closed as early as possible. They
are more common in bitches than dogs. They are also thought to be inherited.
NB: If a hernia is strangulated,
it is a Veterinary emergency, and treatment is needed immediately.
Eye
Disease PPM:- (Persistent Pupillary Membrane)This is where the
foetal membrane of the eye, does not completely reabsorb, as it should. It is a very common disease in the Basenji. What a
puppy is born with, will never become worse, in fact, often it will fade to very little as the dog matures. This membrane
should be gone by the time the pup is approximately 14 days old. It can come in all shapes, sizes and severities,
as well as affecting different parts of the eye. Sometimes it can be seen by the naked eye, (extensive PPM), or it may be
small enough to only be seen by an eye specialist with his specialised equipment. If it is extensive, a reduction in sight,
is possible, and in a very few cases, blindness can occur.
It is believed to be inherited. The exact mode hasn’t
been determined as yet. All pups should have an Ophthalmological assessment at 7-10 weeks, in order to get an accurate diagnosis.
PRA :- (Progressive Retinal Atrophy)This
is an eye condition in which the retina begins to deteriorate, causing a loss of vision, which will lead to blindness. Unfortunately
the Basenji has late onset, (approximately between 4-9 years of age), when often the dog/bitch has already been bred
from. While some breeds that are affected by PRA have a DNA test available, unfortunately the Basenji doesnt at this point
in time. Testing is done by a Veterinary Opthalmologist. Signs and symptoms include, night blindness, (usually
this is the first indication that your dog may be PRA affected), which then leads to gradual day blindness, then total blindness.
Eye examinations should be done yearly. It’s thought to be a simple recessive gene.
ColobomaThis
is an absence, either complete or partial, of a portion of an eye, which occurs in the foetal development. Basenjis are usually
affected on the optic nerve. It is inherited through recessive genes. They generally dont appear to affect a dog’s vision.
It is suggested that dogs diagnosed with Coloboma’s are culled from a breeder’s producing stock.
Cardiac
AssessmentOccasionally Basenji’s have been diagnosed with heart murmurs. These can be diagnosed by a normal
veterinary, but if a diagnosis is made, a Cardiologist assessment is recommended. They should be assessed by your Vet every
2 years or so, as changes can occur at any time in the dogs life. Patella AssessmentAgain,
occasionally Basenji’s have been diagnosed with patella luxation. Diagnosis is able to be done by your Veterinary Surgeon.
They should also be assessed every 2 years or so.
|