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Basenji Health Information

It is known that all breeds of dogs have some inherited diseases, unfortunately. We believe it is our responsibility to screen all breeding stock, prior to engaging in any litters.


People looking into purchasing a Basenji, (or any breed of dog), should educate themselves in which diseases are applicable, and then quiz the breeder/s, that they are interested in, as to what health testing has been done. It’s recommended that you see the copies of all health results of the breeder/dogs you may be looking at.


The following is a list of disease that affects the Basenji, in no particular order:
 

Fanconi Syndrome

Description

Fanconi Syndrome is quite prevalent in the Basenji, but, it is also seen in other breeds and humans as well. It is where the proximal renal tubules, of the kidneys, dont reabsorb nutrients and electrolytes back into the body, so therefore these will ‘spill’ into the urine. The body then loses these vital nutrients needed for normal function.


Some of the signs and symptoms include: - Increased thirst, increased urination, weight loss, muscle wasting, weakness, dehydration, coat changes etc. It should be noted here that some of these signs and symptoms are seen in Diabetes, and until recently, many Basenji’s were misdiagnosed as such, often with disastrous and/or fatal consequences. This disease usually presents after 3 years of age, but has been seen in younger and much older dogs.


While there is no cure for this disease, so long as the dog is diagnosed early, treatment can give these dogs reasonable quality of life. Treatment is usually centred on the replacement of the metabolic deficiencies, i.e. vitamin, mineral and bicarbonate, along with a high protein diet. This treatment has been developed by Dr Steve Gonto, M.M. Sc PhD and more information can be found here.


If this disease is left untreated, it is fatal. Early detection is paramount. A DNA Linkage Test has been released on July 14th 2007, at the University of Missouri. At this point in time it is only a linkage test, but we are hopeful that we will be able to find the actual gene, very soon. There are 4 results that can be achieved: - Probable Clear, Probable Carrier, Probable Affected, and finally, Probable Indeterminate.
Probable Clear; the gene is not present in the dog. They will not pass the gene on.


Probable Carrier; this dog has one copy only, of the gene.


Probable Affected; this dog has 2 copies of the gene. It will develop the disease and will always pass the gene to offspring.


Probable Indeterminate; between Clear-Carrier. This dog should always be regarded as a Carrier, when making breeding plans.


Breeding Pairs:-
Parents; Fanconi Result;
Clear x Clear= 100% clear puppies.
Clear x Carrier= 50% clear, 50% carrier, on average.
Clear x Affected= 100% carrier.
Carrier x Carrier= 25% clear, 50% carrier, 25% affected, on average.
Carrier x Affected= 50% carrier, 50% affected, on average.
Affected x Affected= 100% affected.

 


Haemolytic Anaemia, (Also known as Pyruvate Kinase

Deficiency Haemolytic Anaemia):-

Thankfully this disease has nearly been eliminated, due to thorough testing, by breeders, worldwide.


H.A is where red blood cells are destroyed too quickly. This is due to a lack of an enzyme, called Pyruvate Kinase, (P.K.). Signs and symptoms of the disease include: - the dog tires easily and sleeps more, they may faint, usually have very pale/white gums and will often have ‘golden’ coloured faeces. Dogs will typically die by approximately 2-4 years of age.


A DNA test is available and results are either clear, carrier or affected. There are a few carriers still in the gene pool world-wide, but thankfully this disease is nearly eradicated.IPSID


Hypothyroidism

Hypothyroidism is low levels of Thyroid Hormone found in the blood stream. The thyroid basically controls the metabolism of most cells, in the body. Unfortunately, Basenji’s appear to have quite a high incidence of this disease. The signs and symptoms vary greatly, but will often include: - aggressiveness, weight gain, (or sometimes weight loss), lethargy, infertility, poor coat condition, skin issues, temperature intolerance, (usually to cold), irregular heat cycles etc. There are many other signs and symptoms that may present in the dog, so a thorough evaluation is needed by your Vet, if you suspect this to be a problem in your dog. Treatment is with a thyroid supplement usually given daily, and affected dogs will usually respond very quickly to treatment.


Diagnosis is made via a blood test and it is usually recommended that a full thyroid panel is collected, i.e. T3, Free T3, T4, Free T4, T3AA, T4AA, TSH, (although this is not always recommended), and finally TgAA. At the time that I was testing my dogs for this, I was unable to get the complete test done in Australia, for a reasonable price, so I sent my bloods here...Once the results are known we highly recommend that you send the results to Dr Jean Dodds. Dr Dodds has a particular interest in Hypothyroidism in dogs, and in particular sighthounds. Her vast knowledge in this area is of particular interest to Basenji lovers all around the world. Even if the bloods are taken elsewhere, Dr Dodds is more than happy to read the results, and inform your Vet on an appropriate course of treatment, if need be.


Another test which should be done is the TgAA, for Autoimmune Lymphocytic Thyroiditis. It is believed to be a genetic issue for Basenji’s. It is a single gene disorder, and a recessive trait. A positive result will only be found in dogs which have the 2 genes. Negative results will show no genes. Results are only positive or negative, they will not show carriers, unfortunately. It is advised to test annually until 5-6 years, because if the autoantibodies are not present at this age, it’s unlikely to develop the disease.


Hip/Elbow Dysplasia

Hip Dysplasia is where the hip socket is badly formed, or malformed, which will eventually lead to lameness, and finally arthritis. It’s thought to be polygenic, with multiple genes involved in its expression. It can affect either one or both hips.


Whilst hip dysplasia is not too common in the Basenji, there have been some dysplastic dogs detected, of varying degrees. Breeding stock should be tested, (via x-ray, then these x-rays need to be assessed, and graded by a radiographic specialist),prior to being bred from.


Elbow Dysplasia is also an inherited disease, which primarily affect large breed dogs. It’s not known to be a problem in the Basenji’s. Its characterised by varying degrees of elbow incongruity, bony fragments and finally severe arthritic changes in the elbow region.


The reason I have mentioned it here in the Basenji health section, is because when sedating/anaesthetising the dog for his hip x-rays, it is not a lot more expense to have the elbows done at the same time.

IPSID :- (Immunoproliferative Small Intestine Disease)

This disease over the years has also been known as Basenji Diarrhoea Syndrome, Chronic Intractable Diarrhoea, Malabsorbtion Syndrome, or finally Basenji Enteropathy.


Basically IPSID is a type of inflammatory bowel disease, which results in the dog not being able to absorb nutrients from its food. It is thought to be inherited, but other factors may also predispose dogs to it i.e. physical or emotional stress.


Some of the signs and symptoms include; diarrhoea, weight loss, increase or decrease appetite, flatulence, vomiting, depression, dry coat and skin, and finally hair loss. The type of symptoms and their severity do differ from dog to dog. These dogs have good days and bad days. Prognosis is poor, although it’s thought that Holistic Medicine does/can offer some relief to these dogs. Treatment is mostly aimed at treating the signs and symptoms that the dog displays e.g. vitamin/mineral supplements, antibiotics, prednisolone and also a thorough investigation of the dog’s diet, including an elimination diet.


IPSID :- (Immunoproliferative Small Intestine Disease)

This disease over the years has also been known as Basenji Diarrhoea Syndrome, Chronic Intractable Diarrhoea, Malabsorbtion Syndrome, or finally Basenji Enteropathy.


Basically IPSID is a type of inflammatory bowel disease, which results in the dog not being able to absorb nutrients from its food. It is thought to be inherited, but other factors may also predispose dogs to it i.e. physical or emotional stress.


Some of the signs and symptoms include; diarrhoea, weight loss, increase or decrease appetite, flatulence, vomiting, depression, dry coat and skin, and finally hair loss. The type of symptoms and their severity do differ from dog to dog. These dogs have good days and bad days. Prognosis is poor, although it’s thought that Holistic Medicine does/can offer some relief to these dogs. Treatment is mostly aimed at treating the signs and symptoms that the dog displays e.g. vitamin/mineral supplements, antibiotics, prednisolone and also a thorough investigation of the dog’s diet, including an elimination diet.


Hernia’s

An umbilical hernia is quite a common problem in the Basenji’s. It is a condition in which abdominal contents protrude through the abdominal wall, at the area of the umbilicus. It is often just the fat that protrudes. They are usually quite small and will often decrease in size as the pup grows. They are usually not serious and can be reduced at the time a pup is desexed, or undergoes any other type of anaesthesia. They are thought to be inherited.


Inguinal hernias are uncommon in the Basenji, but they do crop up occasionally. It occurs when the abdominal contents/fat protrude through the inguinal rings, which is located at the inner fold of the rear leg, the groin area. If they are large enough they can affect part of the intestinal loop, the bladder and/or uterus, so it is important that they are closed as early as possible. They are more common in bitches than dogs. They are also thought to be inherited.


NB: If a hernia is strangulated, it is a Veterinary emergency, and treatment is needed immediately.


Eye Disease

 

PPM:- (Persistent Pupillary Membrane)

This is where the foetal membrane of the eye, does not completely reabsorb, as it should. It is a very common disease in the Basenji. What a puppy is born with, will never become worse, in fact, often it will fade to very little as the dog matures. This membrane should be gone by the time the pup is approximately 14 days old.


It can come in all shapes, sizes and severities, as well as affecting different parts of the eye. Sometimes it can be seen by the naked eye, (extensive PPM), or it may be small enough to only be seen by an eye specialist with his specialised equipment. If it is extensive, a reduction in sight, is possible, and in a very few cases, blindness can occur.


It is believed to be inherited. The exact mode hasn’t been determined as yet. All pups should have an Ophthalmological assessment at 7-10 weeks, in order to get an accurate diagnosis.


PRA :- (Progressive Retinal Atrophy)

This is an eye condition in which the retina begins to deteriorate, causing a loss of vision, which will lead to blindness. Unfortunately the Basenji has late onset, (approximately between 4-9 years of age), when
often the dog/bitch has already been bred from. While some breeds that are affected by PRA have a DNA test available, unfortunately the Basenji doesnt at this point in time. Testing is done by a Veterinary Opthalmologist.


Signs and symptoms include, night blindness, (usually this is the first indication that your dog may be PRA affected), which then leads to gradual day blindness, then total blindness. Eye examinations should be done yearly. It’s thought to be a simple recessive gene.

Coloboma

This is an absence, either complete or partial, of a portion of an eye, which occurs in the foetal development. Basenjis are usually affected on the optic nerve. It is inherited through recessive genes. They generally dont appear to affect a dog’s vision. It is suggested that dogs diagnosed with Coloboma’s are culled from a breeder’s producing stock.


Cardiac Assessment

Occasionally Basenji’s have been diagnosed with heart murmurs. These can be diagnosed by a normal veterinary, but if a diagnosis is made, a Cardiologist assessment is recommended. They should be assessed by your Vet every 2 years or so, as changes can occur at any time in the dogs life.

 

Patella Assessment

Again, occasionally Basenji’s have been diagnosed with patella luxation. Diagnosis is able to be done by your Veterinary Surgeon. They should also be assessed every 2 years or so.